Abstract: Nano-silver/poly(2-acrylamido-2-methylpropanesulfonate sodium (PAMPS)) composite was synthesized in situ by microwave radiation without addition of any reducer. The composite was analyzed and characterized by UV-Vis, XRD, FTIR, TEM and XPS. The results show that nano-silver is homogeneously dispersed in PAMPS matrix and possesses face-centered cubic structure. The morphology of nano-silver was not affected by microwave radiation time. It is also found that interactions exist between nano-Ag and nitrogen and carbonyl oxygen atoms in PAMPS, and the thermal stability of PAMPS decreases with nano-Ag dispersion in the composite.