Abstract: In order to research multiobjective optimization for minimizing residual stress, porosity and maximizing interlaminar shear strength during winding of composite prepreg tapes, T300/epoxy resin preprepreg tape winding experiment with four factors and three levels based on Box-Behnken Design (BBD) principle was designed. Based on grey relational analysis (GRA) the multi-objective optimization problem was transformed into a single-objective optimization problem. The influence weights of residual stress, porosity and interlayer shear strength on the grey relational grade(GRG) were determined by principal component analysis(PCA). Through regression analysis of the experimental data, a second-order prediction model of GRG and main winding process parameters was established. The effects of process parameters on residual stress, porosity, interlaminar shear strength and GRG were analyzed, and the optimum scheme of winding process parameters was determined. Response surface methodology (RSM) was used to solve the optimization problem of process parameters and the winding experiment of prepreg tape was carried out. The results show that the optimal combination of the process parameters obtained by this optimization method can effectively improve the residual stress, porosity and interlaminar shear strength, and improve the performance of preg tape winding products.